RESEARCH PROGRAM
Ongoing Research Projects in collaborations with:
1. Collaborator: TMGH, Nagasaki University (Dr. Bhim)
Research title:
Determination of the prevalence of non-vaccine serotypes of pneumonococcus and co-colonization of pneumococcus with respiratory viruses in infants after PCV10 introduction in Bhaktapur, Nepal”
Status: DNA extraction of the samples completed and awaiting for shipping the samples to Japan for qPCR
2. Collaborator: Prof. Christopher M Parry, University of Liverpool, UK
Research title:
Characterization of antimicrobial resistance in bloodstream infection-associated pathogens in pediatric population in Bhaktapur, Nepal
Status: Manuscript writing ongoing
3. Collaborator: Siddhi Memorial Foundation funded research
Research title:
Molecular characterization of Klebsiella pneumoniae isolates originating from pediatric intensive care units to investigate overlap of multidrug resistance and virulence
Status: Data analysis completed
4. Collaborator: Partially funded by SM hospital, Prof Christopher M Parry, and Ashmita’s group (Ashmita Thapa’s master thesis; M Sc Medical Microbiology)
Research title:
Characterization of Transferrable Mechanisms of Quinolone Resistance among quinolone-resistant Escherichia coli and Klebsiella pneumoniae isolates causing UTI among children
Status: Under review for publication
5. Oxford University Clinical Research Unit (OCURU) Vietnam & Nepal
Research Title : The Azithromycin and Cefixime treatment of typhoid in South Asia Trial (ACT-South Asia trial)
“Azithromycin and Cefixime versus Azithromycin alone for the out-patient treatment of
clinically suspected or confirmed uncomplicated typhoid fever in South Asia; A
randomized controlled trial (ACT-South Asia)”,
clinically suspected or confirmed uncomplicated typhoid fever in South Asia; A
randomized controlled trial (ACT-South Asia)”,
Status : Ongoing
6. WHO, Institute of Medicine – Tribhuvan University
Research Title : Nepal Sabin IPV Trial : Comparison of immunogenicity and safety between Sabin and Salk inactivated poliovirus vaccine in the combined bivalent oral poliovirus vaccine schedule: A double blind randomized controlled non-inferiority trial “
Status : Starting from 20th March
7. Stanford University & Dhulikhel Hospital – Kathmandu University
Research Title : Surveillance for Enteric Fever in Asia Project (SEAP) Phase II
Status : Ongoing
8. Nagasaki University & London School of Hygiene & Tropical Medicine
Research Title: Effectiveness of point-of-care lung ultrasound versus chest X-ray for the management of childhood lower respiratory infections in low-resource setting: a single center, pragmatic, open-label, randomized, controlled, non-inferiority clinical trial (ELUS study)
Status : Awaiting NHRC Approval